Description
Our RAD-140 powder is 2g of pure RAD-140 (testolone) for labs that make their own solutions. It’s a nonsteroidal selective androgen receptor modulator (SARM). Sports Technology Labs supplies it for in-vitro research only.
What is RAD-140 (testolone)?
RAD-140 (testolone, also called vosilasarm) is a nonsteroidal SARM developed by Radius Health. In preclinical work it showed strong activity in muscle with much less effect on the prostate and seminal vesicles than testosterone.
Radius later studied it in breast cancer, where it acts on androgen receptors in tumor cells. It isn’t an approved medicine.
The mechanism behind RAD-140
RAD-140 binds the androgen receptor and drives androgen-responsive gene activity in muscle and bone, with partial activity in the prostate. In monkeys it raised lean mass at exposures that left prostate size mostly unchanged.
In ER-positive breast cancer cells, switching on the androgen receptor holds back estrogen-driven growth, which is why Radius tested it there. Rodent work also suggested it protects neurons in culture.
RAD-140 powder specifications
- Compound: RAD-140 (testolone)
- Also known as: testolone, vosilasarm
- CAS number: 1182367-47-0
- Molecular formula: C20H16ClN5O2
- Molecular weight: 393.8 g/mol
- Structure: nonsteroidal benzonitrile with an oxadiazole ring
- Amount: 2g (2,050mg net per pouch)
- Form: crystalline powder in a sealed pouch
- Purity: 97.47% by HPLC, identity by mass spectrometry
- WADA status: prohibited, class S1.2
- Tested by: MZ Biolabs, Tucson, Arizona
- SKU: STL-RAD140-P
- Intended use: laboratory research only
Published studies on RAD-140
The founding paper is Miller and colleagues, ACS Medicinal Chemistry Letters, 2011, which described RAD-140’s discovery and its tissue selectivity in rats and monkeys.
A phase 1 trial in women with advanced ER-positive, HER2-negative breast cancer reported its pharmacokinetics and side effects, including liver enzyme rises in some patients.
You can read the original papers through this PubMed search at the U.S. National Library of Medicine.
RAD-140 compared with similar compounds
Quick context: RAD-140 is a potent nonsteroidal SARM from Radius Health, later tested in breast cancer. Other compounds in the same area:
- Ostarine is the most studied SARM, with human trial data on muscle wasting
- LGD-4033 binds the androgen receptor very tightly and has a phase 1 study in healthy men
- RAD-150 is a benzoate ester of RAD-140 with no published studies of its own
- S4 (andarine) is an early partial-agonist SARM from GTx with rat data on muscle and bone
- S23 is a high-affinity SARM studied as a male contraceptive in rats
All of them bind the androgen receptor, but affinity, selectivity and the amount of published data differ a lot. Compare them in our SARM powders.
RAD-140 powder purity and lab testing
The current certificate of analysis shows 97.47% by HPLC. The testing is done by MZ Biolabs, an independent lab in Tucson, Arizona, which also checks identity by mass spectrometry.
The COA image is in the product gallery at the top of this page, so you can read the batch result before you order.
Why two tests? A sample can be very pure and still be the wrong compound. HPLC measures purity and mass spec confirms the molecular weight, so together they cover both problems.
If anything arrives wrong, the 60-day money-back guarantee covers it.
How labs prepare RAD-140 powder
The pouch holds 2,050mg of crystalline RAD-140, slightly more than the stated 2g. Use a calibrated analytical balance and an anti-static spatula, because fine powder sticks to plastic.
Most labs dissolve it in PEG-400 to make a stock solution. Some example strengths:
- 2000mg in 50mL gives 40mg/mL
- 2000mg in 100mL gives 20mg/mL
Stir until clear, then store the solution in glass, not plastic.
Keeping RAD-140 powder dry
Keep the pouch sealed, dry and out of light at room temperature or cooler. Moisture is the main thing to avoid, so reseal it straight after weighing.
More from our SARM powders
- PEG-400 (Polyethylene Glycol 400) 60mL, the solvent for making your own solutions
- RU-58841 Powder 2g, the antiandrogen as bulk powder
- Cardarine Powder (GW-501516) 2g, the PPAR-delta agonist as bulk powder
- RAD-150 Powder (TLB-150) 2g, the SARM ester as bulk powder
- S23 Powder 2g, the SARM as bulk powder
The rest of the range is in our SARM powders. Every section of the store is linked from the Sports Technology Labs home page.
Common questions about RAD-140 powder
How much is in a pouch of RAD-140 powder?
2,050mg net, a little over the 2g on the label.
Can RAD-140 powder be used in people or animals?
No. Sports Technology Labs sells it for laboratory research only. It isn’t approved for human or veterinary use.
Is RAD-140 powder in stock?
Yes. RAD-140 powder is in stock and ships free worldwide.
Where can I buy RAD-140 powder?
Right here at Sports Technology Labs. Add it to your cart on this page and check out. Shipping is free on every order.
Is there a discount on RAD-140 powder?
Yes. Pay with crypto at checkout and you get 15% off your order.
Order RAD-140 powder online today
RAD-140 powder is in stock at $102.99 per pouch, with free worldwide shipping. Add it to your cart and check out in a minute. Pay with crypto and you save 15%.
More options for this research area are in our SARM powders.
Sports Technology Labs sells this product for laboratory and in-vitro research only. It isn’t a medicine, food or dietary supplement, and it must not be given to people or animals. The FDA has not evaluated any statement on this page. RAD-140 is on the World Anti-Doping Agency prohibited list (S1.2, anabolic agents), so tested athletes should not handle it outside a lab. Buyers must be 21 or older.
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