S23 Powder 2g

Description

S23 powder from Sports Technology Labs is 2g of S23 as dry crystalline powder in a sealed pouch. S23 is a nonsteroidal selective androgen receptor modulator (SARM). It’s sold for laboratory research only.

What is S23?

S-23 is a nonsteroidal SARM of the aryl-propionamide class, made in the University of Tennessee lab of James Dalton and Duane Miller, the same group behind ostarine and andarine. It binds the androgen receptor very tightly, with a reported Ki of about 1.7 nanomolar.

It was designed as a possible male contraceptive, so most of what’s known about it comes from that line of rat work. It has never been tested in a published human trial.

The mechanism behind S23

S-23 binds the androgen receptor in muscle, bone and the prostate. The receptor complex moves into the nucleus and switches on androgen-responsive genes, the same route testosterone uses.

Because the binding is so strong, S-23 also signals back to the hypothalamus and pituitary, and LH and FSH fall sharply. That feedback is the basis of the contraception research and the reason labs track hormone levels in any S-23 model.

S23 powder product details

• Compound: S23
• CAS number: 1010396-29-8
• Molecular formula: C18H13ClF4N2O3
• Molecular weight: 416.8 g/mol
• Structure: nonsteroidal aryl-propionamide
• Amount: 2g (2,050mg net per pouch)
• Form: crystalline powder in a sealed pouch
• Purity: 99.8% by HPLC, identity by mass spectrometry
• WADA status: prohibited, class S1.2
• Tested by: MZ Biolabs, Tucson, Arizona
• SKU: STL-S23-P
• Intended use: laboratory research only

What the literature says about S23

Jones and colleagues described S-23 in Endocrinology in 2009. In male rats, S-23 with a small dose of estradiol benzoate suppressed sperm production, and fertility came back about 100 days after it was stopped. The same rats kept or gained muscle and bone mass while fat mass fell.

The study also showed strong suppression of LH and FSH, which is how S-23 shuts down sperm production. In castrated rats it acted as a full agonist in muscle and only a partial one in the prostate.

Every study mentioned here is indexed on PubMed, the free database run by the NIH. Try this S-23 search.

Where S23 fits in the range

Quick context: S23 is a high-affinity SARM studied as a male contraceptive in rats. Other compounds in the same area:

• Ostarine is the most studied SARM, with human trial data on muscle wasting
• LGD-4033 binds the androgen receptor very tightly and has a phase 1 study in healthy men
• RAD-140 is a potent nonsteroidal SARM from Radius Health, later tested in breast cancer
• RAD-150 is a benzoate ester of RAD-140 with no published studies of its own
• S4 (andarine) is an early partial-agonist SARM from GTx with rat data on muscle and bone

All of them bind the androgen receptor, but affinity, selectivity and the amount of published data differ a lot. Compare them in our SARM powders.

How labs prepare S23 powder

S23 powder ships as crystalline powder in a sealed pouch with a net weight of 2,050mg, a little over the 2g on the label. Weigh it on an analytical balance; kitchen scales aren’t accurate enough at these amounts.

To make a liquid stock, dissolve a weighed amount in PEG-400. For example:

• 2000mg in 50mL gives 40mg/mL
• 2000mg in 100mL gives 20mg/mL

Warm the solvent slightly and stir until no crystals remain. A magnetic stirrer saves time.

Storing S23 powder

Store the powder in its resealed pouch in a cool, dry, dark place. Adding a desiccant packet to a secondary container helps in humid labs.

How Sports Technology Labs tests S23 powder

The current certificate of analysis shows 99.8% by HPLC. The testing is done by MZ Biolabs, an independent lab in Tucson, Arizona, which also checks identity by mass spectrometry.

You’ll find the COA in the photo gallery above. Open it and check the date, the method and the purity figure yourself.

Both numbers matter. Purity by HPLC means little if nobody checked the identity, and that’s the job mass spectrometry does.

Orders are covered by a 60-day money-back guarantee.

Products often ordered with S23 powder

• SR-9009 Powder (Stenabolic) 2g, the REV-ERB agonist as bulk powder
• RAD-150 Powder (TLB-150) 2g, the SARM ester as bulk powder
• Andarine Powder (S4) 2g, the SARM as bulk powder
• RAD-140 Powder (Testolone) 2g, the SARM as bulk powder
• LGD-4033 Powder (Ligandrol) 2g, the SARM as bulk powder

Want the whole catalog? Open our SARM powders, or start from the Sports Technology Labs home page.

Common questions about S23 powder

How much is in a pouch of S23 powder?

2,050mg net, a little over the 2g on the label.

What do I dissolve S23 powder in?

Most labs use PEG-400, which we also sell.

How should S23 powder be stored?

Sealed, dry and away from light, at room temperature or cooler.

Can S23 powder be used in people or animals?

No. Sports Technology Labs sells it for laboratory research only. It isn’t approved for human or veterinary use.

Is S23 powder in stock?

Yes. S23 powder is in stock and ships free worldwide.

Get S23 powder from Sports Technology Labs

The powder is in stock at $67.99 per pouch, with free worldwide shipping. Add it to your cart and check out in a minute. Pay with crypto and you save 15%.

More options for this research area are in our SARM powders.

Sports Technology Labs sells this product for laboratory and in-vitro research only. It isn’t a medicine, food or dietary supplement, and it must not be given to people or animals. The FDA has not evaluated any statement on this page. S23 is on the World Anti-Doping Agency prohibited list (S1.2, anabolic agents), so tested athletes should not handle it outside a lab. Buyers must be 21 or older.