Description
Our MK-677 powder is 2g of pure MK-677 (ibutamoren) for labs that make their own solutions. It’s an orally active nonpeptide growth hormone secretagogue. Sports Technology Labs supplies it for in-vitro research only.
Background on MK-677 (ibutamoren)
MK-677 (ibutamoren) is an orally active, nonpeptide growth hormone secretagogue developed by Merck. It mimics ghrelin at the GHS-R1a receptor, raising growth hormone and IGF-1. It’s often sold next to SARMs, but it isn’t one.
It was never approved as a medicine, and it’s on the WADA prohibited list.
What MK-677 does in cells
MK-677 binds GHS-R1a, the same receptor as ghrelin and the GHRP peptides, in the pituitary and hypothalamus. That boosts the size of natural GH pulses and lifts IGF-1 from the liver.
Because it’s a small molecule, not a peptide, it survives digestion and lasts about a day, which is what made it attractive as an oral research tool. The same receptor drives hunger, so appetite goes up too.
MK-677 powder product details
- Compound: MK-677 (ibutamoren)
- CAS number: 159634-47-6
- Molecular formula: C27H36N4O5S
- Molecular weight: 528.7 g/mol
- Structure: spiro-piperidine small molecule (supplied as the mesylate salt)
- Amount: 2g (2,050mg net per pouch)
- Form: crystalline powder in a sealed pouch
- Purity: 99.87% by HPLC, identity by mass spectrometry
- WADA status: prohibited, class S2
- Tested by: MZ Biolabs, Tucson, Arizona
- SKU: STL-MK677-P
- Intended use: laboratory research only
Published studies on MK-677
Nass and colleagues ran a two-year trial in healthy older adults, published in the Annals of Internal Medicine in 2008. MK-677 raised GH and IGF-1 to levels seen in young adults and increased fat-free mass, with rises in fasting glucose noted.
Earlier Merck studies by Chapman and colleagues described how it raises GH while keeping the normal pulse pattern.
Every study mentioned here is indexed on PubMed, the free database run by the NIH. Try this MK-677 search.
MK-677 compared with similar compounds
Quick context: MK-677 is an oral ghrelin mimic that raises GH and IGF-1 and isn’t a SARM. Other compounds in the same area:
- Tesamorelin is a stabilized GHRH analog with clinical trial data on abdominal fat
- Ipamorelin is the most selective ghrelin receptor agonist, releasing GH with little change in cortisol or prolactin
- Sermorelin is the first 29 amino acids of natural GHRH, broken down within minutes
- CJC-1295 DAC is a GHRH analog that binds albumin through its drug affinity complex and lasts for days
- GHRP-6 is a ghrelin receptor agonist known for a strong hunger signal alongside GH release
GHRH analogs and ghrelin receptor agonists act on two different pituitary receptors, which is why studies so often pair them. Compare them in our growth hormone peptides.
How Sports Technology Labs tests MK-677 powder
Every batch is sent to MZ Biolabs in Tucson, Arizona, before it goes on sale. They run HPLC for purity and mass spectrometry to confirm identity. The latest certificates for this product read 99.87%.
Scroll through the product photos and the certificate is there, with the test date and the chromatogram.
Why two tests? A sample can be very pure and still be the wrong compound. HPLC measures purity and mass spec confirms the molecular weight, so together they cover both problems.
If anything arrives wrong, the 60-day money-back guarantee covers it.
How labs prepare MK-677 powder
You get 2,050mg of MK-677 as dry crystalline powder, which is the cheapest way to buy it per milligram. Accurate work needs an analytical balance that reads to 0.1mg.
Most labs dissolve it in PEG-400 to make a stock solution. Some example strengths:
- 2000mg in 50mL gives 40mg/mL
- 2000mg in 100mL gives 20mg/mL
Gentle warmth and patient stirring dissolve it fully. Check the bottom of the container for undissolved crystals before you bottle it.
MK-677 powder storage
Keep the pouch sealed, dry and out of light at room temperature or cooler. Moisture is the main thing to avoid, so reseal it straight after weighing.
More from our SARM powders
- RAD-150 Powder (TLB-150) 2g, the SARM ester as bulk powder
- PEG-400 (Polyethylene Glycol 400) 60mL, the solvent for making your own solutions
- Andarine Powder (S4) 2g, the SARM as bulk powder
- S23 Powder 2g, the SARM as bulk powder
- YK-11 Powder 1g, the steroidal SARM as bulk powder
The rest of the range is in our SARM powders and growth hormone peptides. Every section of the store is linked from the Sports Technology Labs home page.
Common questions about MK-677 powder
How much is in a pouch of MK-677 powder?
2,050mg net, a little over the 2g on the label.
Is there a discount on MK-677 powder?
Yes. Pay with crypto at checkout and you get 15% off your order.
Where is the MK-677 powder lab report?
In the product gallery. MZ Biolabs tested the batch and the posted purity is 99.87%.
What do I dissolve MK-677 powder in?
Most labs use PEG-400, which we also sell.
How should MK-677 powder be stored?
Sealed, dry and away from light, at room temperature or cooler.
Buy MK-677 powder at Sports Technology Labs
Ready to order? MK-677 powder costs $97.99, it’s in stock and shipping is free. Paying in crypto takes 15% off.
More options for this research area are in our SARM powders and growth hormone peptides.
Sports Technology Labs sells this product for laboratory and in-vitro research only. It isn’t a medicine, food or dietary supplement, and it must not be given to people or animals. The FDA has not evaluated any statement on this page. MK-677 is on the World Anti-Doping Agency prohibited list (S2, peptide hormones, growth factors and mimetics), so tested athletes should not handle it outside a lab. Buyers must be 21 or older.
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