Description
Liquid MK-677 is a 30mL bottle of MK-677 (ibutamoren) at 25mg/mL, tested to 99.87% purity. MK-677 is an orally active nonpeptide growth hormone secretagogue. It’s sold for laboratory research only.
What is MK-677 (ibutamoren)?
MK-677 (ibutamoren) is an orally active, nonpeptide growth hormone secretagogue developed by Merck. It mimics ghrelin at the GHS-R1a receptor, raising growth hormone and IGF-1. It’s often sold next to SARMs, but it isn’t one.
It was never approved as a medicine, and it’s on the WADA prohibited list.
The mechanism behind MK-677
MK-677 binds GHS-R1a, the same receptor as ghrelin and the GHRP peptides, in the pituitary and hypothalamus. That boosts the size of natural GH pulses and lifts IGF-1 from the liver.
Because it’s a small molecule, not a peptide, it survives digestion and lasts about a day, which is what made it attractive as an oral research tool. The same receptor drives hunger, so appetite goes up too.
Liquid MK-677 product details
- Compound: MK-677 (ibutamoren)
- CAS number: 159634-47-6
- Molecular formula: C27H36N4O5S
- Molecular weight: 528.7 g/mol
- Structure: spiro-piperidine small molecule (supplied as the mesylate salt)
- Concentration: 25mg/mL
- Volume: 30mL glass bottle (750mg total)
- Carrier: USP-grade PEG-400
- Included: graduated 1mL glass pipette
- Purity: 99.87% by HPLC, identity by mass spectrometry
- WADA status: prohibited, class S2
- Tested by: MZ Biolabs, Tucson, Arizona
- SKU: STL-MK677-L
- Intended use: laboratory research only
What the literature says about MK-677
Nass and colleagues ran a two-year trial in healthy older adults, published in the Annals of Internal Medicine in 2008. MK-677 raised GH and IGF-1 to levels seen in young adults and increased fat-free mass, with rises in fasting glucose noted.
Earlier Merck studies by Chapman and colleagues described how it raises GH while keeping the normal pulse pattern.
You can read the original papers through this PubMed search at the U.S. National Library of Medicine.
MK-677 and its alternatives
In one line, MK-677 is an oral ghrelin mimic that raises GH and IGF-1 and isn’t a SARM. The compounds researchers most often weigh it against:
- Tesamorelin is a stabilized GHRH analog with clinical trial data on abdominal fat
- Ipamorelin is the most selective ghrelin receptor agonist, releasing GH with little change in cortisol or prolactin
- Sermorelin is the first 29 amino acids of natural GHRH, broken down within minutes
- CJC-1295 DAC is a GHRH analog that binds albumin through its drug affinity complex and lasts for days
- GHRP-6 is a ghrelin receptor agonist known for a strong hunger signal alongside GH release
GHRH analogs and ghrelin receptor agonists act on two different pituitary receptors, which is why studies so often pair them. Compare them in our growth hormone peptides.
How Sports Technology Labs tests Liquid MK-677
Sports Technology Labs doesn’t test its own products. MZ Biolabs in Tucson, Arizona, does, using HPLC for purity and mass spectrometry for identity. For this listing the posted result is 99.87%.
Scroll through the product photos and the certificate is there, with the test date and the chromatogram.
HPLC and mass spec answer different questions. HPLC tells you what share of the sample is the main compound. Mass spec tells you the compound is the right molecule. A COA with only one of them leaves a gap.
If anything arrives wrong, the 60-day money-back guarantee covers it.
Liquid MK-677 concentration and measuring
Liquid MK-677 comes in a 30mL glass bottle at 25mg/mL, so there are 750mg of MK-677 in the bottle. The carrier is USP-grade PEG-400, and a 1mL glass pipette is included.
Measuring is simple arithmetic: 0.5mL holds 12.5mg and 0.1mL holds 2.5mg. Read the pipette at eye level, since PEG-400 is thick and clings to the glass.
Storing Liquid MK-677
Keep the bottle tightly closed in a cool, dry place out of direct sunlight. The amber or UV-resistant glass helps, but a cupboard is better than a windowsill.
Clean and dry the pipette after each use, or keep a separate one for each bottle.
Related to Liquid MK-677
- Liquid YK-11 10mg/mL, a steroidal SARM ready to measure
- Liquid SR-9009 (Stenabolic) 20mg/mL, an REV-ERB agonist ready to measure
- Liquid MK-777 (Acetamoren) 20mg/mL, a GH secretagogue ready to measure
- Liquid Ligandrol (LGD-4033) 10mg/mL, an SARM ready to measure
- Liquid S23 20mg/mL, an SARM ready to measure
Browse the full list in our liquid SARMs and growth hormone peptides, or go back to the Sports Technology Labs home page to see every category.
Liquid MK-677 FAQ
How much MK-677 is in a bottle of Liquid MK-677?
750mg: 30mL at 25mg/mL.
Can Liquid MK-677 be used in people or animals?
No. Sports Technology Labs sells it for laboratory research only. It isn’t approved for human or veterinary use.
Is Liquid MK-677 in stock?
Yes, Liquid MK-677 is in stock today.
Where can I buy Liquid MK-677?
Right here at Sports Technology Labs. Add it to your cart on this page and check out. Shipping is free on every order.
Is there a discount on Liquid MK-677?
Yes. Pay with crypto at checkout and you get 15% off your order.
Order Liquid MK-677 online today
Ready to order? This solution costs $67.99, it’s in stock and shipping is free. Paying in crypto takes 15% off.
Compounds that fit the same study sit in our liquid SARMs and growth hormone peptides.
Sports Technology Labs sells this product for laboratory and in-vitro research only. It isn’t a medicine, food or dietary supplement, and it must not be given to people or animals. The FDA has not evaluated any statement on this page. MK-677 is on the World Anti-Doping Agency prohibited list (S2, peptide hormones, growth factors and mimetics), so tested athletes should not handle it outside a lab. Buyers must be 21 or older.







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