Description
MOTS-c 5mg is 5mg of MOTS-c in a sealed glass vial, tested to 99.66% purity. MOTS-c is a mitochondrial-derived peptide. Sports Technology Labs supplies it for in-vitro research only.
What is MOTS-c?
MOTS-c is a 16-amino-acid peptide coded not in the cell nucleus but in mitochondrial DNA, inside the gene for the 12S ribosomal RNA. Changhan Lee and colleagues in Pinchas Cohen’s lab at the University of Southern California described it in 2015.
It belongs to a small group of mitochondrial-derived peptides, alongside humanin, that act as signals from the mitochondria to the rest of the cell and body.
How MOTS-c works
Most proteins are coded in the cell nucleus. MOTS-c is one of a handful of peptides coded in mitochondrial DNA instead. Its main target looks like the folate cycle, which feeds into AMPK activation and better glucose handling in muscle.
Under stress it can move into the nucleus and change gene expression. Circulating levels drop with age in both mice and people, which is why it’s studied in metabolism and aging.
MOTS-c 5mg technical data
- Compound: MOTS-c
- CAS number: 1627580-64-6
- Molecular formula: C101H152N28O22S2
- Molecular weight: 2,174.6 g/mol
- Structure: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Amount: 5mg per vial
- Form: lyophilized powder in a sterile glass vial (diluent not included)
- Purity: 99.66% by HPLC, identity by mass spectrometry
- Tested by: MZ Biolabs, Tucson, Arizona
- SKU: STL-MOTSC-5
- Intended use: laboratory research only
MOTS-c research findings
The 2015 Cell Metabolism paper reported that MOTS-c prevented diet-induced obesity and insulin resistance in mice, working mainly through skeletal muscle.
Reynolds and colleagues reported in Nature Communications in 2021 that exercise raises MOTS-c levels in people, and that treating older mice with it improved their physical performance.
Every study mentioned here is indexed on PubMed, the free database run by the NIH. Try this MOTS-c search.
Where MOTS-c fits in the range
MOTS-c is a short peptide coded in mitochondrial DNA and linked to AMPK. Here’s how the nearest options in our range differ:
- AOD-9604 is a modified 176-191 fragment of growth hormone, studied for fat breakdown without GH’s growth effects
- Tesamorelin is a stabilized GHRH analog with clinical trial data on abdominal fat
Each one reaches fat metabolism from a different side: a GH fragment, the mitochondria or the GHRH receptor. Compare them in our weight loss peptides.
MOTS-c 5mg purity and lab testing
Every batch is sent to MZ Biolabs in Tucson, Arizona, before it goes on sale. They run HPLC for purity and mass spectrometry to confirm identity. The latest certificates for this product read 99.66%.
You’ll find the COA in the photo gallery above. Open it and check the date, the method and the purity figure yourself.
Why two tests? A sample can be very pure and still be the wrong compound. HPLC measures purity and mass spec confirms the molecular weight, so together they cover both problems.
You also get a 60-day money-back guarantee on the order.
MOTS-c 5mg mixing guide
Working out the strength of your solution is one division: 5mg over the volume you add. Common volumes give these results:
- 1mL of diluent gives 5mg per mL
- 2mL of diluent gives 2.5mg per mL
- 3mL of diluent gives 1.667mg per mL
Bacteriostatic water is the usual diluent, and it isn’t in the box. Add it along the glass wall, a little at a time, then swirl until the solution is clear.
Keeping MOTS-c 5mg stable
Keep the sealed vial in the fridge at 2 to 8°C, away from light and heat. Once mixed, keep MOTS-c 5mg refrigerated, use it within 30 days and don’t freeze the solution.
Write the date mixed and the concentration on the vial before it goes back in the fridge.
Related to MOTS-c 5mg
- AOD-9604 5mg, an hGH fragment
- Tesamorelin Peptide, a GHRH analog
- Epitalon 10mg, a tetrapeptide
- GHK-Cu Copper Peptide 50mg, a copper peptide
- SS-31 10mg (Elamipretide), a mitochondrial peptide
The rest of the range is in our weight loss peptides and anti-aging peptides. Every section of the store is linked from the Sports Technology Labs home page.
Common questions about MOTS-c 5mg
How much is in each MOTS-c 5mg vial?
5mg of freeze-dried powder per vial.
Where is the MOTS-c 5mg lab report?
In the product gallery. MZ Biolabs tested the batch and the posted purity is 99.66%.
Does MOTS-c 5mg come with diluent?
No. Diluent and lab supplies aren’t included, and most labs use bacteriostatic water.
How should MOTS-c 5mg be stored?
In the fridge at 2 to 8°C before and after mixing. Use the mixed solution within 30 days and don’t freeze it.
Can MOTS-c 5mg be used in people or animals?
No. Sports Technology Labs sells it for laboratory research only. It isn’t approved for human or veterinary use.
Order MOTS-c 5mg online today
Ready to order? The peptide costs $59.99, it’s in stock and shipping is free. Paying in crypto takes 15% off.
Building a bigger order? See our weight loss peptides and anti-aging peptides.
Sports Technology Labs sells this product for laboratory and in-vitro research only. It isn’t a medicine, food or dietary supplement, and it must not be given to people or animals. The FDA has not evaluated any statement on this page. Buyers must be 21 or older.
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